Purpose: The aim of this research was to analyze knowledge, attitudes, and compliance with antiretroviral (ARV) antidotes among HIV patients at the Central Bangka Regional General Hospital.

Methods: This study used a qualitative method with a phenomenological approach. The technique for taking respondents was a non-probability sampling technique, purposive sampling. Nine informants participated in 9 people. The data were collected using an in-depth interview guide.

Results: Findings from the research show that there were still several informants who had insufficient knowledge about compliance in taking ARV antidotes. Even though the informants' attitude towards compliance with antiretroviral (ARV) antiretrovirals was relatively good, there were several key informants who stated that they had stopped taking antiretroviral (ARV) antidotes for several months because they felt healthy. However, several months later, they experienced adverse effects that resulted in a decline in their health.

Recommendation: Based on the findings of this research, it is recommended that the Person in Charge of HIV at the Central Bangka Regional Hospital should increase the level of supervision of HIV patients with the aim of ensuring that they remain compliant, consistent, and sustainable in taking HIV antidotes. The Central Bangka Health Service is also advised to improve cross-program coordination in HIV prevention efforts as well as to monitor the schedule for taking ARV antidotes through collaboration with health workers and those in charge of HIV patients at the Central Bangka District Hospital.